- About Pediatric Bioscience
- Autism & Autism Spectrum Disorder
- Maternal Antibody Related Autism
- The MAR Test
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The MAR Test is an informational test which determines if an individual has an increased chance of having a child with autism. The test involves analyzing a blood sample for the presence of antibodies that react with specific proteins found in the fetal brain. Antibodies specific for these proteins are only observed in mothers who have had a child with autism.
The immune system produces protective proteins called antibodies after encountering something foreign to the body, such as a bacterium or a virus. Antibodies are designed to recognize the foreign entity, known as an ‘antigen’, with high specificity. After an antibody recognizes and binds an antigen, the immune system will begin to eliminate it from the body. Sometimes, the immune system mistakenly produces antibodies that react with the body’s own tissues. This is called an autoimmune response. Rheumatoid arthritis, multiple sclerosis and lupus are examples of autoimmune disorders that involve antibodies specific for 'self-antigens.'
The MAR Test is currently in development, with the plan for commercial availability the first half of 2013. If you would like your name placed on an email list to get updates on our progress, please provide your email address here.
If you are interested in participating in the final development of the MAR Test prior to its commercial launch, contact us at firstname.lastname@example.org